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  • CDK9抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW9975
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :1mg/100ug
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中文名稱:CDK9抗原(重組蛋白)

英文名稱:
CDK9 Antigen (Recombinant Protein)

儲(chǔ)      存:
冷凍(-20℃)

相關(guān)類別:抗原

概述

Fusion protein corresponding to a region derived from 19-315 amino acids of human CDK9


技術(shù)規(guī)格

Full name:

cyclin-dependent kinase 9

Synonyms:

TAK, C-2k, CTK1, CDC2L4, PITALRE

Swissprot:

P50750

Gene Accession:

BC001968

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.


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