購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)：兔抗CAPN6多克隆抗體
英文名稱(chēng)： Anti-CAPN6 rabbit polyclonal antibody
別 名： calpain 6; CANPX; CAPNX; CalpM; DJ914P14.1
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： CAPN6
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. |
|
Applications: |
ELISA, WB |
|
Name of antibody: |
CAPN6 |
|
Immunogen: |
Fusion protein of human CAPN6 |
|
Full name: |
calpain 6 |
|
Synonyms: |
CANPX; CAPNX; CalpM; DJ914P14.1 |
|
SwissProt: |
Q9Y6Q1 |
|
ELISA Recommended dilution: |
5000-10000 |
|
WB Predicted band size: |
75 kDa |
|
WB Positive control: |
Rat heart tissue, A172 cell, NIH/3T3 cell, TM4 cell lysates |
|
WB Recommended dilution: |
500-2000 |
