購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
TLR5 |
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Immunogen: |
Synthetic peptide of human TLR5 |
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Full name: |
toll-like receptor 5 |
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Synonyms： |
SLE1; TIL3; SLEB1; MELIOS |
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SwissProt: |
O60602 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
25-100 |
