購(gòu)物車(chē)
幫助
021-54845833/15800441009
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Background: |
SRGAP1 (Slit-robo Rho GTPase activating protein 1), also known as ARHGAP13 (Rho GTPase activating protein 13), functions as a GTPase-activating protein for Cdc42 and Rho A. Expressed in kidney, testis, lung and brain, SRGAP1 contains an FCH (Fes/CIP4 homology) domain, a Rho-GAP domain and an SH3 domain. In the presence of Slit, SRGAP1 (via its SH3 domain) binds to the CC3 motif in robo (a protein responsible for mediating the repulsive effect of Slit) with higher affinity and inhibits Cdc42 activity in a robo/SRGAP-dependent manner. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SRGAP1 |
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Immunogen: |
Synthetic peptide of human SRGAP1 |
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Full name: |
SLIT-ROBO Rho GTPase activating protein 1 |
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Synonyms： |
ARHGAP13 |
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SwissProt: |
Q7Z6B7 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
25-100 |
