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中文名稱： 兔抗PTK2B(Phospho-Tyr579) 多克隆抗體
英文名稱： Anti-PTK2B(Phospho-Tyr579) rabbit polyclonal antibody
別 名： PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： PTK2B(Phospho-Tyr579)
反應(yīng)種屬： Human Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Applications: |
WB, IHC |
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Name of antibody: |
PTK2B(Phospho-Tyr579) |
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Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 579(E-D-Y(p)-Y-K) derived from Human PYK2. |
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Full name: |
protein tyrosine kinase 2 beta |
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Synonyms： |
PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK |
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SwissProt: |
Q14289 |
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IHC positive control: |
Human brain tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
116 kDa |
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WB Positive control: |
NIH/3T3 cells and HepG2 cells lysates |
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WB Recommended dilution: |
500-1000 |
