購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： 兔抗TXNIP多克隆抗體
|
Background: |
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
TXNIP |
|
Immunogen: |
Synthetic peptide of humanTXNIP |
|
Full name: |
thioredoxin interacting protein |
|
Synonyms： |
THIF; VDUP1; HHCPA78; EST01027 |
|
SwissProt: |
Q9H3M7 |
|
ELISA Recommended dilution: |
2000-10000 |
|
IHC positive control: |
Human esophagus cancer |
|
IHC Recommend dilution: |
30-150 |
