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  • PCID2抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17966
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :100ug
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中文名稱: PCID2抗原(重組蛋白)

英文名稱: PCID2 Antigen (Recombinant Protein)

別       名: PCI domain containing 2; F10

儲       存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to C terminal 200 amino acids of human PCID2

技術(shù)規(guī)格

Full name:

PCI domain containing 2

Synonyms:

F10

Swissprot:

Q5JVF3

Gene Accession:

BC016614

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

PCID2 is expressed in immature and early-stage B lymphocytes and regulates expression of the mitotic checkpoint protein MAD2. Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).

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