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  • NFKBIA抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17750
    • 應用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :1mg/100ug
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中文名稱: NFKBIA抗原(重組蛋白)

英文名稱: NFKBIA Antigen (Recombinant Protein)

儲      存: 冷凍(-20℃)

相關類別: 抗原

概述

Fusion protein corresponding to a region derived from 1-317 amino acids of human NFKBIA

技術規(guī)格

Full name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Synonyms:

IKBA; MAD-3; NFKBI

Swissprot:

P25963

Gene Accession:

BC004983

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

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