Name: NEDD4L抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： NEDD4L抗原（重組蛋白）

英文名稱： NEDD4L Antigen (Recombinant Protein)

別名： neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; RSP5; NEDD4-2; NEDD4.2; hNEDD4-

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to C terminal 250 amino acids of human NEDD4L

技術規(guī)格

Full name:	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
Synonyms:	RSP5; NEDD4-2; NEDD4.2; hNEDD4-2
Swissprot:	Q96PU5
Gene Accession:	BC032597
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.

ELISA試劑盒

PCR試劑盒