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  • NECTIN4抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17736
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :100ug
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中文名稱(chēng): NECTIN4抗原(重組蛋白)

英文名稱(chēng): NECTIN4 Antigen (Recombinant Protein)

別       名: nectin cell adhesion molecule 4; LNIR; PRR4; EDSS1; PVRL4; nectin-4

儲(chǔ)       存: 冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概述

Fusion protein corresponding to a region derived from 371-510 amino acids of human NECTIN4

技術(shù)規(guī)格

Full name:

nectin cell adhesion molecule 4

Synonyms:

LNIR; PRR4; EDSS1; PVRL4; nectin-4

Swissprot:

Q96NY8

Gene Accession:

BC010423

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]

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