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  • REN抗原(重組蛋白)

    規(guī)格:
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17622
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :1mg/100ug
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中文名稱(chēng):REN抗原(重組蛋白)

英文名稱(chēng) REN Antigen (Recombinant Protein)

別      名: HNFJ2

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類(lèi)別: 抗原

概  述:

Fusion protein corresponding to C terminal 300 amino acids of human REN


技術(shù)規(guī)格:

Full name:

renin

Synonyms:

HNFJ2

Swissprot:

P00797

Gene Accession:

BC047752

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined.


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