Name: MCM3抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： MCM3抗原（重組蛋白）

英文名稱： MCM3 Antigen (Recombinant Protein)

別名： HCC5, P1.h, RLFB, P1-MCM3

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to C terminal 300 amino acids of human MCM3

技術(shù)規(guī)格

Full name:	minichromosome maintenance complex component 3
Synonyms:	HCC5, P1.h, RLFB, P1-MCM3
Swissprot:	P25205
Gene Accession:	BC001626
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

ELISA試劑盒

PCR試劑盒