中文名稱：DOK1抗原（重組蛋白）

英文名稱：DOK1 Antigen (Recombinant Protein)

儲存：冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to C terminal 300 amino acids of human DOK1

技術(shù)規(guī)格

Full name:

docking protein 1, 62kDa (downstream of tyrosine kinase 1)

Synonyms:

P62DOK

Swissprot:

Q99704

Gene Accession:

BC114440

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

021-54845833/15800441009

ELISA試劑盒

PCR試劑盒

生化試劑盒

農(nóng)殘檢測試劑盒

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基礎(chǔ)培養(yǎng)基

完全培養(yǎng)基

原代細胞

細胞專用培養(yǎng)基

細胞系

菌株

生化試劑

病理染色液

科研抗體

標(biāo)準(zhǔn)品

血清

形態(tài)病理檢測

分子病理

超微病理

細胞凋亡與檢測

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相關(guān)文章

DOK1抗原（重組蛋白）

Full name:	docking protein 1, 62kDa (downstream of tyrosine kinase 1)
Synonyms:	P62DOK
Swissprot:	Q99704
Gene Accession:	BC114440
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.