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  • DCN抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW10393
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :1mg/100ug
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中文名稱:DCN抗原(重組蛋白)

英文名稱:DCN Antigen (Recombinant Protein)

儲      存:冷凍(-20℃)

相關(guān)類別:抗原

概述

Fusion protein corresponding to a region derived from 60-359 amino acids of human DCN


技術(shù)規(guī)格

Full name:

decorin

Synonyms:

CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B

Swissprot:

P07585

Gene Accession:

BC005322

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.



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